Why the test is performed
To detect or quantify the BCR::ABL1 fusion associated with specific myeloid and lymphoid leukaemias.
World time
Laboratory Testing Online / Molecular Pathology
BCR::ABL1 Molecular Test
To detect or quantify the BCR::ABL1 fusion associated with specific myeloid and lymphoid leukaemias.Test profileMOBCR::ABL1 Molecular Test
Test and specimen
What is being examined?
- Test
- BCR::ABL1 Molecular Test
- Department
- Molecular Pathology
- Typical sample or measurement
- EDTA blood or bone marrow
Before the test
Specialist haematology ordering and serial testing at defined time points are required for meaningful trends.
Clinical interpretation
Laboratory results should be interpreted by a qualified professional using the correct reference interval, method, symptoms, history and other findings. A normal or abnormal value rarely confirms or excludes a condition by itself.
What the test is used for
Supporting diagnosis and monitoring molecular response to treatment using standardised reporting where applicable.
How the test is performed
RNA is extracted, converted to complementary DNA and measured by reverse-transcription quantitative PCR with controls and calibrated reporting.
Conditions and diseases considered
Used particularly in chronic myeloid leukaemia and selected acute lymphoblastic leukaemia pathways.
Recommended further tests
CBC and film, bone-marrow examination, chromosome analysis/FISH, flow cytometry and mutation testing for resistant disease.
Primary public reference
Continue with the official patient guide.
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