Why the test is performed
To look for pathogenic variants associated with inherited or tumour-related cancer risk.
World time
Laboratory Testing Online / Molecular Pathology
BRCA1/BRCA2 Genetic Test
To look for pathogenic variants associated with inherited or tumour-related cancer risk.Test profileMOBRCA1/BRCA2 Genetic Test
Test and specimen
What is being examined?
- Test
- BRCA1/BRCA2 Genetic Test
- Department
- Molecular Pathology
- Typical sample or measurement
- Blood, saliva or validated tumour specimen depending on purpose
Before the test
Pre-test counselling and informed consent are essential; consider implications for relatives, privacy and insurance law in the relevant country.
Clinical interpretation
Laboratory results should be interpreted by a qualified professional using the correct reference interval, method, symptoms, history and other findings. A normal or abnormal value rarely confirms or excludes a condition by itself.
What the test is used for
Risk assessment, family counselling and selected treatment decisions when clinical criteria are met.
How the test is performed
DNA is extracted and analysed by sequencing with deletion/duplication methods as appropriate; variants are classified under recognised frameworks.
Conditions and diseases considered
Used in hereditary breast, ovarian, prostate and pancreatic cancer pathways. A variant result requires expert interpretation.
Recommended further tests
Genetic counselling, confirmatory/family testing, broader hereditary-cancer panels or tumour biomarkers.
Primary public reference
Continue with the official patient guide.
COHSEW has summarised this information for navigation and awareness. Follow the source and your healthcare provider’s current instructions for the complete context.
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