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Molecular Laboratory Clinic / Diagnostic discipline

Biochemistry

Translate concentrations of enzymes, metabolites, proteins, electrolytes and hormones into clinically useful patterns.
Modern biochemistry laboratory workflow
BiochemistryCOHSEW laboratory perspective

Purpose and scope

Evidence designed for the decision.

Clinical biochemistry supports screening, diagnosis, monitoring and risk assessment. Fasting status, collection time, posture, medicines, haemolysis and other pre-analytical factors can affect results, which must be read with reference intervals and the person’s clinical context.

Scope noteAvailability, recognised methods and accreditation status must be confirmed for the exact laboratory, location, test and sample type before use.

Specialist capabilities

A connected technical programme.

Panels are selected after the question, sample matrix, applicable limits, required sensitivity and reporting purpose are understood.

01

Core chemistry

Electrolytes, renal, liver, bone and metabolic profiles.

02

Cardiometabolic health

Glucose control, lipids and selected cardiovascular markers.

03

Endocrinology

Thyroid and other hormone pathways selected for the clinical question.

04

Nutritional status

Iron, vitamin and protein markers with appropriate interpretive limits.

Samples and evidence

Defined matrices.
Controlled handling.

Correct container, identity, preservation, temperature, transport and holding time are agreed before collection.

01Serum02Plasma03Urine04Whole blood05Timed collections06Specialist referral specimens

The laboratory pathway

01

Confirm request, consent and patient identification

02

Collect and transport the correct specimen

03

Examine with validated methods and quality controls

04

Authorise, interpret and communicate the report

Authoritative framework

Primary guidance for quality and practice.

COHSEW summarises these sources; it does not reproduce standards or replace current national rules and competent professional judgement.

Need a programme for Biochemistry?

Define scope, samples and decision criteria with a specialist.

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