World time

Molecular Laboratory Clinic / Diagnostic discipline

Cytology

Assess individual cells and small cell groups from screening, fluid and needle-sampling pathways.
Modern cytology laboratory workflow
CytologyCOHSEW laboratory perspective

Purpose and scope

Evidence designed for the decision.

Cytology can provide minimally invasive diagnostic or screening information. Adequate sampling, prompt preparation, clinical context and correlation with imaging or histology are important because cellular material may be limited or unrepresentative.

Scope noteAvailability, recognised methods and accreditation status must be confirmed for the exact laboratory, location, test and sample type before use.

Specialist capabilities

A connected technical programme.

Panels are selected after the question, sample matrix, applicable limits, required sensitivity and reporting purpose are understood.

01

Cervical cytology

Screening pathways integrated with HPV testing according to national programmes.

02

Fine-needle aspiration

Cellular assessment from palpable or image-guided lesions.

03

Body-fluid cytology

Assessment of pleural, peritoneal, cerebrospinal and other fluids.

04

Urine and respiratory cytology

Targeted cellular evaluation with risk-led ancillary testing.

Samples and evidence

Defined matrices.
Controlled handling.

Correct container, identity, preservation, temperature, transport and holding time are agreed before collection.

01Cervical samples02Fine-needle aspirates03Urine04Body fluids05Respiratory samples06Brushings and washings

The laboratory pathway

01

Confirm request, consent and patient identification

02

Collect and transport the correct specimen

03

Examine with validated methods and quality controls

04

Authorise, interpret and communicate the report

Authoritative framework

Primary guidance for quality and practice.

COHSEW summarises these sources; it does not reproduce standards or replace current national rules and competent professional judgement.

Need a programme for Cytology?

Define scope, samples and decision criteria with a specialist.

Talk to the laboratory team ↗